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Stem Cell Transplant in Treating Diabetic Nephropathy

Treating Diabetic Nephropathy with cord blood stem cell has been accepted by patients gradually, because the stem cell has many unmatched advantages on treating Diabetic Nephropathy compare with the traditional therapies. Stem Cells Transplant is an effective method to relieve patients’ pains. How does Stem Cells treat Diabetic Nephropathy? Let us know the details from follows:

The advantages of treating Diabetic Nephropathy with cord blood stem cell are as follows:

1. Multipotent stem cell with highly proliferation and multi-differentiation is undoubtedly the best seed cell to obtain a large number of Pancreatic B Cells, and can solve the problem of deficient islet cells to a great extent.

2. Another advantage is that the islet cell differentiated by stem cell can play the role of regulating blood sugar physiologically.

3. Pancreatic stem cell differentiated by one’s own can decrease the immunological rejection, without the restriction of social ethics of embryonic stem cell.

4. As the rapid development and application of basic Medicine, including Cytology, Molecular biology, etc. multiple types of stem cells as the seed cells differentiating into B cells through inducement come true.

Stem cell during the treatment of diabetic complications achieved certain progress, especially the powerful advantages of cord blood stem cell treating diabetic nephropathy have attracted many patients’ notice.

The advantages of using cord blood stem cell to treat diabetes compared with mesenchymal stem cells (MSCs)

(1)Compared with MSCs (mesenchymal stem cells), cord blood stem cell avoid the problem of ethics while treating diabetes.

(2)Cord blood stem cells only express a small number of type 1 diabetes molecules, less express or don’t express Costimulatory Molecule of type 2 diabetes or T cells. Low immunogenicity of MSCs can escape from the long time survival of the immune surveillance system in the diabetes patients’body, inhibit the growth of dendritic cells, inhibit T cell proliferation, and is a type of immune cells with special permission.

(3) The experiment on cord blood stem cells treating diabetes, the cell present positive reaction. It is proved that, the cord blood cell is relatively naïve, life cycle is short, is without the unlimited multiplication capacity of cancer, and is safe as transplantation stem cells.

Stem Cells Transplant can maximally restore these damaged cells and these pathological cells, block the process of renal fibrosis, reduce serum creatinine, and alleviate these complications like renal anemia, high blood pressure and edema etc. As a result, the indicator of protein and occult blood decrease obviously even turn negative, Stem Cells Transplant prolongs the time interval of dialysis, even let patients get rid of dialysis.

Article Source: http://www.articlemotron.com

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